Comparison of quality of anesthetic effect between intramuscularly administered ketamine, intravenously administered ketamine and intravenously administered propofol in diazepam premedicated goats

Research Abstract

This study aimed to evaluate intramuscularly administered ketamine, intravenously administered ketamine and intravenously administered propofol in diazepam premedicated goats. Nine native female goats divided into three groups (each of 3 goats) were premedicated with diazepam 1 mg/kg intramuscularly. Goats of group I were treated with ketamine (8 mg/kg) intravenously, while those of group II treated with ketamine (10 mg/kg) intramuscularly, and group III injected with propofol (5 mg/kg) intravenously. The mean anesthetic onset, anesthetic duration, and total recovery period were calculated. The mean heart rate (HR), respiratory rate (RR), rectal temperature (RT) and biochemical parameters also were recorded. Satisfactory anesthesia and immobilization (smooth induction, and smooth recovery) needed for surgical interventions of short duration were achieved in all groups. The induction was good and smooth in groups I and III. The quality of recovery was good in groups III and I and recovery is longer in group II. In conclusion, this study indicates that the 3 regimens are associated with acceptable anesthetic characteristics; Propofol IV is superior to ketamine because it provides uneventful onset and recovery which are more rapid than ketamine IV or ketamine IM, so reduces anaesthetic risk while administration of ketamine intravenously is superior to its administration intramuscularly.

Research Keywords

Diazepam, ketamine, propofol, intra-venous, intra-muscular, goat