Non-acidic 1,3,4-trisubstituted-pyrazole derivatives as lonazolac analogs with promising COX-2 selectivity, anti-inflammatory activity and gastric safety profile

Research Abstract

This thesis comprises four chapters. The first one is an introduction that comprises a hint on biological view of inflammation and different drugs used in its treatment. It also includes the different methods adopted to synthesize some diaryl and triarylheterocycles with apyrazole, pyrazolineor pyridine ascentral ring.

Research Keywords

pyrazol