Phytochemical and Biological Studies on Erythrina crista-galli L. Grown in Egypt

Research Abstract

The leaves and stem bark of Erythrina crista-galli (L.) family: leguminosae were investigated for their steroidal and flavonoidal contents. β-amyrine, stigmasterol, β-sitosterol and β-sitosterol glucoside were isolated from the leaves. Erycristin, Sandwicensin and Erythrabyssin II pterocarpans were isolated from the stem bark. The compounds were identified using chemical and spectral methods (U.V., mass spectroscopy, 1HNMR and 13CNMR The hydro-alcoholic and the aqueous extract of the leaf showed significant analgesic, antipyretic, anti-inflammatory and antioxidant activities while the hydro-alcoholic extract of the stem bark showed significant anti-microbial activity especially against methicillin resistant Staphylococcus aureus (MRSA).

Research Keywords

Key words: Erythrina crista-galli, N-nororientaline, erythrinine, erycristin, sandwicensin, erythrabyssin II, MRSA and anticancer