Synthesis of certain acridine derivatives as anticancer agents

Research Abstract

Compound Xh showed the highest in vitro cytotoxic activity against colon cancer cell line HCT-116 but compound Xb had the highest in vitro cytotoxic activity against liver cancer cell line HepG-2. Also compounds VIIa&b & Xh showed nearly the same activity as doxorubicin against breast cancer cell line MCF-7.

Research Keywords

Acridine-cancer-doxorubicin