CURRICULUM VITAE (CV)
Name: Nilly Helmy Abdalla, M.D.
Contact Address: Internal medicine Dept., Beni Suef University Hospital, Beni Suef University, Egypt.
Home Tel: 086 2090335 Mobile: 0101371835
E-mail: nillyhelmy@yahoo.com nilyhelmy@gmail.com
Personal Data
Date of Birth: 01 Augst, 1971
Place of birth: Minia, Egypt
Nationality: Egyptian
Family Status: Married, 4 children
Education
Bachelor of Medicine and Surgery (M.B.B.Ch.): Grade very good, Faculty of Medicine, Minia University, Egypt, December 1994.
Master Degree (M.Sc.) in Internal medicine, Internal medicine Dept., Faculty of Medicine, Minia University, Egypt, June 1999. M.Sc. thesis title: “Assessment of insulin sensitivity in patients with chronic hepatitis C”.
MRCP, UK, First Part: 2001
M.D. in Internal medicine, Internal medicine Dept., Faculty of Medicine Minia University, July 2009. M.D. thesis title “Study of Some Adipocytokines and Insulin Resistance in Metabolically Obese, Normal-weight Individuals (MONW)”
- English IELTs degree, grade 7 out of 9, 2006
PROFESSIONAL EXPERIENCE:
01/03/1995–29/02/1996 House-officer, Minia University Hospital, El-Minia, Egypt.
3/1996–3/8/1998 Resident, Internal medicine Dept, Minia University Hospital, Minia University, Egypt.
4/8/1998– July 2010 Specialist, Internal medicine Dept., Minia University Hospital, Minia University Egypt.
July 2010 till now; Lecturer of Internal medicine. Internal medicine Dept, Beni Suef University, Egypt.
Experience
Management of different cases of medicine as liver, kidney, heart, peptic ulcer, neurology, haematology…..
Writing master and M.D. thesis
Carry out of scientific research concerning diabetes mellitus and hepatitis C
Referees
1. Prof. Khalid Alseid Fouad Alhadidi, Professor and head of Internal medicine Dept, Faculty of Medicine,Beni Suef University, Beni Suef, Egypt
- Prof. Eglal Mahmmoud Mohammad Shawky, Professor of Internal medicine Dept, Faculty of Medicine, Minia University,El-Minia, Egypt, Tel No, 0105601025
2- Prof Noussa Mahmoud El-Adwy Nassef, Professor of Internal medicine Dept, Faculty of Medicine, Minia University, El-Minia, Egypt.
3- Prof. Mahmoud A. El-Rehani, Professor and head of Biochemistry Dept, Vice dean of Faculty of Medicine, Minia University,El-Minia, Egypt. Tel No, 0106970154
Hepatitis c is one of the most endemic diseases in Egypt. There is increase in the prevalence of diabetes in chronic hepatitis c. This trial aimed to find if there is an insulin resistant in chronic hepatitis C. trying to found the relation between insulin resistance, chronic hepatitis c and B cell function
Patient and Method: the study conducted on 20 patients with chronic hepatitis c and twenty volunteers with the matched age and sex
Bothe group subjected to the following
1. Full history and clinical examination
2. Hepatitis B and C virus by ELISA
3. Hepatitis C PCR
4. Liver function test
5. Fasting blood sugar
6. Post Prandial blood sugar
7. Measurement of insulin resistance
8. Assessment of B cell function
9. Liver biopsy
Result:
There was statistically deference between patient group and control group in insulin resistance and beta cell function .this mean that there is Hyperinsulinemia in chronic hepatitis c. There was statistically high deference between patient group and control group in beta cell function. As beta cell function was high in chronic hepatitis patient
Study of Some Adipocytokines and Insulin Resistance in Metabolically Obese, Normal-weight Individuals (MONW)
Study of Some Adipocytokines and Insulin Resistance in Metabolically Obese, Normal-weight Individuals (MONW)
Adipose tissue secretes a number of proinflammatory cytokines, as interleukin-6. IL-6 appears to play an important role in mediating insulin resistance. Insulin resistance is strongly associated with atherosclerosis and frequently coexists with common proatherogenic disorders. Insulin resistance has been suggested to play a central role in the pathogenesis of metabolic syndrome and diabetes mellitus. The metabolic syndrome was applied to those individuals who have three of the following criteria hypertriglyceridemia, low HDL-cholesterol, hypertension, type 2 diabetes mellitus and central obesity.
MONW individuals, despite having a normal or slightly elevated BMI display metabolic characteristics that may contribute to the development of the metabolic syndrome.
In this research, we tried to study the state of the insulin resistance in MONW individuals and the role of some adipocytokines in the development of MONW syndrome.
Patient and method: Group one (patients group) consisted of twenty patients, who was fulfilling the criteria of MONW (9 female and 11 male), while the control group was consisting of twenty age and sex, matched healthy volunteers
We measure of Fasting serum insulin, calculate insulin resistance according to HOMA model, measure of serum adiponectin and measure serum interleukin-6 using standard ELISA kit.
Result; Serum adiponectin was low in MONW individuals. There was also a positive correlation between serum adiponectin and HDL-C in both groups.Serum level of IL-6 was found to be higher in MONW individuals group in comparison to normal individuals group. There was a negative correlation between serum adiponectin and serum levels of interleukin-6 in patients group more than the control group. Insulin resistance was higher in MONW group. There was a negative correlation between serum adiponectin level and insulin resistance in control and patients groups. Plasma adiponectin levels reduced in non-obese humans, particularly those with visceral obesity, and to correlate inversely with insulin resistance and IL-6.
Conclusion: We concluded that high IL-6 and low adiponectin levels could indicate insulin resistance in MONW individuals. Also IL-6 and adiponectin concentrations were related to fat mass distribution in the MONW