Basic Informations

C.V

CURRICULUM VITAE

 

 

Name: Amira Mohamed Taher Hegazy

Nationality: Egyptian      Date of Birth: June 2, 1974.

Current Position: Lecturer of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.

Home Address: Ishraqua Compound, El-shameliat 6^th October City, Giza, Egypt.

Office Address: Faculty of Pharmacy, Beni-Suef University, Egypt.

Cell Phone: +2 01013518060/ 01011886718

E-mail Address: amira.hegazy@pharm.bsu.edu.eg

University Website: www.bsu.edu.eg

Educational History

• Diploma in the International Negotiation and Diplomacy, the International Electronic University, May 2016.
• Training Course in National Security and Strategy Studies, the Egyptian Nasser Higher Military Academy (Defense Ministry), May 2017.
• Training Course in Crisis and Negotiation Management, the Egyptian Nasser Higher Military Academy (Defense Ministry), August 2017.
• Training Course in Decision Makers and Leadership, the Egyptian Nasser Higher Military Academy (Defense Ministry), July 2018.
• Philosophy of Doctor (Ph.D) of Pharmaceutical Sciences (Analytical Chemistry) Faculty of Pharmacy, Cairo University, May 2012.
• Master of Pharmaceutical Sciences (Analytical Chemistry) Faculty of Pharmacy, Cairo University, December 2002.
• Bachelor of Pharmaceutical sciences, Faculty of Pharmacy, Cairo University, May 1996.

Occupational Background:

• Lecturer in Analytical Chemistry, Faculty of Pharmacy, Beni-Suef University, Egypt.                   (2012-2020).
• Assistant Lecturer in Analytical Chemistry Department, - Faculty of Pharmacy, Beni-Suef University, Egypt. (2003-2012).
• Demonstrator in Analytical Chemistry Department, Faculty of of Pharmacy, Beni-Suef University, Egypt. (1997-2002).

Research Interest:

• Chromatographic methods (including HPLC, HPTLC, UPLC and LC-MS).
• Spectrophotometric and spectrofluorimetric methods.
• Multivariate analysis.
• Studying drug stability in raw material and in their pharmaceutical preparations.
• Analysis of drugs in raw materials, pharmaceutical formulations and biological fluids, whether in mixtures or in presence of metabolites, impurities or degradation products.
• Food chemistry and nutrition.
• Environmental analytical chemistry.

 

Publications:

®  Studying the compatibility of a metoclopramide-HCl–paracetamol mixture via IHCMC and establishing a validated RP-HPLC method for its determination in tablets

AM Hegazy, R Loebenberg, NY Hassan, FH Metwally, M Abdel-Kawy

Analytical Methods 5 (15), 3714-3720

Impact factor: 2.378

https://pubs.rsc.org/en/content/articlelanding/2013/ay/c3ay40731d#!divAbstract

®  Application and Validation of Two Smart Spectrophotometric and a HP-TLC Densitometric Methods for Determination of Metoclopramide Hydrochloride/ Paracetamol in Raw Material and in Pharmaceuticals

MA Amira M. Hegazy, Nagiba Y. Hassan, Fadia H. Metwally

International Journal of Pharmacy 3 (3), 470 – 481

file:///C:/Users/admin/Desktop/own%20papers/AH%20MCP-PCM%20spectro%20tlc%20international%20journal%20of%20pharmacy%20ISSN%20%202249-1848%20CODEN%20%20IJP%20L6.pdf

®  Establishment and validation of Two Smart UV-Spectrophotometric and a Novel Spectrodensitometric Methods for Simultaneous Determination of Metoclopramide Hydrochloride/ Pyridoxine Binary Mixture in Raw Material and in Syrup 

Amira M. Hegazya, Nagiba Y. Hassan, Fadia H. Metwally, Mohammad Abdel-Kawy

International Journal of Pharmacy 3 (3), 490 – 500

file:///C:/Users/admin/Desktop/own%20papers/AH%20MCP-VB6%20spectro%20tlc%20international%20journal%20of%20pharmacy%20ISSN%20%202249-1848%20CODEN%20%20IJP%20L6.pdf

®  Development and validation of two robust simple chromatographic methods for estimation of tomatoes specific pesticides’ residues for safety monitoring prior to food processing line and evaluation of local samples

Amira M. Hegazy, Rehab M. Abdelfatah, Hamada M. Mahmoud, Mohamed A. Elsayed

Food Chemistry, Volume 306, 15 February 2020, 125640

Impact factor: 5.449

https://doi.org/10.1016/j.foodchem.2019.125640

®  Green spectrophotometric approaches for simultaneous analysis of tomato pesticides in commercial formulations and environmental samples

RehabM.Abdelfataha, HamadaM.Mahmoud, MohamedA.Elsayed, AmiraM.Hegazy

Microchemical Journal 152 (2020) 104305

Impact factor: 2.233

file:///C:/Users/admin/Desktop/PROMOTION%20PAPERS/article%204%20(Microchemical%20J.).pdf

 

®  Two spectrophotometric methods for quantitative determination of some pesticides applied for cucumber in Egypt

AM Hegazy, RM Abdelfatah, HM Mahmoud, MA Elsayed

Beni-Suef University Journal of Basic and Applied Sciences, 7 (2018) 598–605

file:///C:/Users/admin/Desktop/PROMOTION%20PAPERS/Article%204%20%20(Beni-Suef%20University%20Journal%20of%20Basic%20and%20Applied%20Sciences).pdf

®  Two chromatographic methods for the quantitative determination of some pesticides applied for cucumber pests in Egypt

RM Abdelfatah, AM Hegazy, HM Mahmoud, MA Elsayed

Separation Science Plus, 1, 5 (2018), 334-342

file:///C:/Users/admin/Desktop/PROMOTION%20PAPERS/Article%203%20%20(Journal%20of%20Separation%20Science%20Plus).pdf

®  Resolution of the spectra of acetamiprid, flutolanil and etofenprox residues for their analysis in tomato fruits

Rehab M.Abdelfatah, Hamada M.Mahmoud, Mohamed A.Elsayed, Amira M.Hegazy

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 238, 9 (2020),118444

https://www.sciencedirect.com/science/article/abs/pii/S1386142520304224?via%3Dihub (https://doi.org/10.1016/j.saa.2020.118444)

Conferences Participation

1-Attendance of The 1^st International Scientific Conference of Faculty of Pharmacy, Beni Suef University entitled" Pharmacy in the Cutting-Edge: Facing Future Challenges". April 2018.

2-Poster presented in The 2^nd International Scientific Conference of Faculty of Pharmacy, Beni Suef University entitled" Pharmacy in the Cutting-Edge: Facing Future Challenges". April 2019.

“Spectrophotometric methods for quantitative determination of pesticides residues after simple and efficient extraction from tomato fruits”

Amira M. Hegazy, Rehab M. Abdelfatah, Hamada M. Mahmoudb, and Mohamed A. Elsayed

3- Attendance of The 5^th FUE International Conference of Pharmaceutical Scinences, at Royal Maxim Palace Kempiniski, First Settlement, Cairo, Egypt. Jan 28-30, 2019.

4-Poster presented in The 4^th International Scientific Conference of Faculty of Pharmacy, Beni Suef University entitled "Enviromental Pollutions Risks in Developing Countries (EPRDC 2020) ". March 3-4, 2020.

“Environmental Approach: Recommended Field Sampling for Verified Specific Chromatographic Assays of a Residual Mixture of Pesticides on Tomato Fruits”

Amira M. Hegazy, Rehab M. Abdelfatah, Hamada M. Mahmoud, and Mohamed A. Elsayed

5- Poster presented in The 1^st International Scientific Conference of School of Pharmacy, New Giza University entitled" Biologics & Biosimilars Symposium". March 9-12, 2020.

“Novel Fast and Eco-Friend GC-MS Technique for Concurrent Estimation of Malignance Patient’s Antiemetic/ Palliative Combination and application to spiked Human Plasma”.

Amira M. Hegazy

6-      Attendance of “Photo- Chemistry and its Application in Pharmacy and Drug Photo-degradation” Conference & workshop, Photo- Chemistry Centre, Faculty of Science, Ein-Shams University, Egypt, June 1998.

7-      Attendance of “Application of Advanced Nanotechnology in Pharmaceutics” Seminar, University of Alberta, Canada, Feb. 2010.

8-      Attendance of “Factors affecting the stability of drug in different forms” Conference, NODCAR, Egypt, Jul. 1997.

9-      Attendance of “Application of Chemometry in Drug Analysis” conference, Cairo University, Egypt, April 1999.

10-  Attendance of “Health between Nutrition and Treatment” International Conference, Beni Suef University, Egypt, May 2002.

General certificates:

• International Computer driving License (ICDL).
• international TOEFL iBT score: 82.

Membership:

• Member in the Egyptian General Syndicate of Pharmacists.
• Member in Cairo Syndicate of Pharmacists.
• Member in the Egyptian Club of Judges.
• Member in Shooting Club.
• Member in Egyptian Union at Edmonton.
• Editor in editorial board of many journals:

*        Open Access Journal of Biomedical Science (OAJBMS)

*        MedRead Journal of Chemistry

*        Journal of Biomedical Science

 

Main managerial responsibilities:

• Foundation of Analytical Chemistry Department in Faculty of Pharmacy- Beni Suef University.
• Foundation and direction of Alumni Department in Faculty of Pharmacy- Beni Suef University.
• Creation and leadership of the Alumni council.

 

Teaching Experience:

• Teaching and supervising the practical courses of pharmaceutical analytical Chemistry for the undergraduate students (first, second, fourth & fifth year) in Faculty of Pharmacy, Beni-Suef University general and clinical pharmacy programs.
• Oral examiner for undergraduate students in Faculty of pharmacy Beni-Suef University and in other public and private universities.
• Teaching and supervising in pharmaceutical analytical Chemistry for the postgraduate students in Faculty of Pharmacy, Beni-Suef University.
• Supervising many of master and Ph.D students (Pharmaceutical analytical chemistry and Medicinal Chemistry).
• Working as academic advisor for clinical pharmacy program students (since 2010).
• Supervising the summer training of undergraduate students at Faculty of Pharmacy, Beni-Suef University.

Scientific Courses:

Under graduate students

• General and physical chemistry
• Photo-chemistry
• Qualitative analysis (analysis of cations and anions)
• Volumetric analysis (acid base, precipitmetry, complexometry, redox analysis)
• Environmental analysis
• Chromatography courses (HPLC principles& applications in pharmaceutical analysis).
• Instrumental analysis (principles and applications of different instrumental techniques in pharmaceutical analysis e.g. Spectroscopic methods (spectrophotometry, Spectrofluorimetry, Atomic absorption…etc), chromatographic methods (HPLC, GC, TLC…etc), electrochemical methods (conductometry, potentiometry…etc)).
• Quality control and quality assurance in pharmaceutical industry.
• Electrochemical methods of analysis (conductometry, potentiometry…etc).
• Food chemistry

Premaster courses:

1-      Advanced methods of instrumental analysis (IR, MS and NMR spectrometry and spectrophotometry).

2-      Quality control in pharmaceutical industry.

3-      Separation analysis techniques (GC, TLC, HPLC, UPLC, LC-MS and Electrophoresis).

4-      Stability indicating methods of analysis.

5-      Thermal stability and analysis.

Other Scientific Activities

*        Reviewing of many manuscripts for different journals, for examples, Open Access Journal of Biomedical Science and Beni-Suef University Journal of Basic and Applied Sciences.

*        Attendances of many scientific seminars and workshops at University of Alberta, Cairo University, Suize Canal University and Beni Suef University.

Master Title

The Analysis of Some Drugs Containing Nitrogen atom"

Master Abstract

English summary for the master thesis Establishing Stability Indicating Methods for Analysis of Some Nitrogen Containing Drugs and Stability Studying of These Drugs The objects of the thesis were to develop simple, accurate and selective stability indicating methods for the quantitative determination of the drugs: a)- Omeprazole (OPZ): anti-peptic ulcer. b)- Meloxicam (MXC): non steroidal anti-inflammatory (NSAID) . some of the suggested methods were used in the kinetic studies of the mentioned drugs according to the conditions specified by FDA guideline. The thesis comprised six parts Part I It contained general introduction as follow: 1. The importance of studying the stability of the drugs, generally. 2. Illustration of the international documents used in stability testing of the drugs and method validation. 3. Common causes of the chemical degradation of the drugs. 4. Solution kinetics. 5. Techniques used as stability indicating methods. Part II It comprised establishment of stability indicating methods for determination of OPZ and MXC in a buffer solution (pH=7.5) and in 0.1N H2SO4 aqueous solution, frequently, in presence of the acid induced degradation products and using these methods in studying the stability of the mentioned drugs in low pHs media, in studying the effect of the heat on the reaction rate and in calculation of the activation energy. a) D1RS for determination of OPZ was established. The measurement was at ?max 265nm. The recovery % was 100 ± 1.6. b) D2R and D3R for determination of MXC were established. The measurement were at ?max 326.5and 423nm, frequently. The recoveries % were 100.13 ± 0.63 and 99.9 ± 0.74, frequently. Part III It comprise establishment of stability indicating methods for determination of OPZ in presence the acid induced degradation products by three different methods as follow: a) HPLC: The conditions were C18, methanol, deionized water, triethylamine and phosphoric acid by the ratio (770:330: 5: 0.8 v/v/v/v) and UV detection at 302nm (*). The recovery % was 100.55 ± 1.63. b) TLC: The conditions were silica gel F254 , ammonia solution 25% and water by the ratio (1: 15 v/v) saturated with n-butanol and UV detection at 280nm (#). The recovery % was 100.41 ± 1.76. c) D2R and D3R: The measurement were at ?max (310 & 330nm) and (319.5 & 335nm), frequently. The recoveries % were 99.98 ± 0.40, 99.99 ± 0.21, 100.10 ± 0.40 and 99.94 ± 0.34, frequently. Part IV It comprised establishment of stability indicating methods for determination of OPZ and MXC in presence of the oxygen induced degradation products and using these methods in studying the stability of the mentioned drugs in oxygenated solution (3% O2) and in studying the effect of the heat and pH on the reaction rate. a) D3R for determination of OPZ was established. The measurement was at ?max 263nm. The recovery % was 99.94 ± 0.39. b) D1R for determination of MXC was established. The measurement was at ?max 394.55nm. The recovery % was 100.36 ± 0.39. c) TLC for determination of MXC. The conditions were silica gel F254 , ethyl acetate, methanol and ammonia solution 25% by the ratio (8.5: 1: 0.5 v/v/v) and UV detection at 320nm (+). The recovery % was 99.80 ± 1.80. Part V It comprised establishment of stability indicating methods for determination of OPZ and MXC in presence of the light induced degradation products and using these methods in studying the stability of the mentioned drugs when exposed to UV radiation) and in studying the effect of the oxygen and pH on the reaction rate. a) D2R for determination of OPZ was established. The measurement was at ?max 330nm. The recovery % was 100.09 ± 0.53. b) D2R for determination of MXC was established. The measurement was at ?max 415nm. The recovery % was 99.67 ± 0.83. Part VI It comprised establishment of stability indicating methods for determination of OPZ and MXC in presence of the UV induced degradation products. a) TLC for determination of MXC. Under the conditions (+). The recovery % was 100.53 ± 0.41. b) TLC for determination of OPZ. Under the conditions (#). The recovery % was 99.99 ± 0.78. c) HPLC for determination of OPZ. Under the conditions (*). The recovery % was 100.19 ± 0.22. d) D1RS for determination of OPZ was established. The measurement was at ?max 309.5nm. The recovery % was 100.60 ± 0.43. the statistical comparisons and the statistical analysis of the data were applied. These statistical studies were illustrated in 40 tables. These proved that the suggested methods are applicable for determination of the mentioned drugs in presence of their different types of degradation products and in their pharmaceutical products, separately. The thesis comprised 76 figures, 40 tables and 182 references and finished by Arabic summary.

PHD Title

Analysis of Some GIT Drugs

PHD Abstract

(Abstract) The thesis covers analysis of the anti-emetic drug; metoclopramide hydrochloride (MCP-HCl) mixtures either with other drugs like paracetamol (PCM) or pyridoxine (VB6) or with products resulting from its degradation. MCP-HCl/ PCM mixture has been proposed via three techniques; spectrophotometry, densitometry and high performance liquid chromatography: Ratio Subtraction and Third Derivative Spectrophotometric methods, Densitometric Method and HPLC Method. MCP-HCl/ VB6 mixture has been suggested via the three mentioned techniques: Isosbestic Point and Derivative Ratio Spectrophotometric Method, Densitometric Method and HPLC Method. Moreover, compatibilities of these mixtures have been examined via calorimetery. MCP-HCl stability in acid medium and highly oxygenated medium has been investigated in this thesis and identification of the degradation products has been recognized. Moreover analysis of the drug in presence of acid induced and H2O2 induced degradation products have been established by the same techniques: Chemometry; Principal component and Partial Least Squares Methods, Densitometric Method and: HPLC Method. Key Words metoclopramide hydrochloride- paracetamol - pyridoxine - products resulting from degradation- spectrophotometry- densitometry - high performance liquid chromatography