البيانات الاساسيه

السيره الذاتيه

أحمد عبد الرحمن حفنى عبد الله
مدرس مساعد
قسم الكيمياء الدوائية
كلية الصيدلة 
جامعة بنى سويف
CURRICULUM VITAE
Ahmed Abdelrahman Hefny
I. Campus Address
Faculty of Pharmacy, Beni-Suef University
Beni-Suef, Egypt
Postal Code: 62514
Tel. 082 2319397 (work)
01000541747 (mobile)
Fax. 082 317953
E-mail: dr.ahmedhefney12@yahoo.com
ahmedhefny@pharm.bsu.edu.eg
II. Personal Information
• Born on September 1st, 1990, Egypt.
• Married.
III. Education
• M.Sc. in Pharmaceutical Sciences (Medicinal chemistry), Faculty of Pharmacy, Cairo University, Egypt, 2017.
• B. Ph. Sc., (Bachelor degree in Pharmaceutical Science), excellent Faculty of Pharmacy, Cairo University [Beni suef branch], Egypt, 2012.
IV. Dissertations
• M.Sc.: Synthesis of indole derivatives as indomethacin analogues.
V. Area of Specialization
Organic Synthesis, Medicinal Chemistry.
VI. Employment history:
Apr., 2013 to date: Demnostrator of medicinal chemistry department, Faculty of Pharmacy, Beni-Suef University, Egypt.
VII. Teaching experience:
• Teaching practical organic pharmaceutical courses for undergraduate students from 2013 to date.
VIII. Training programs (FLDP):
• Preparing proposals, Nov. 14th – Nov. 16th (2009).
• Teaching evaluation, June 17th – June 19th (2006).
• Efficient communication skills, June 10th – June 12th (2006).
• Syllabus design, April 26th – April 27th (2006).
• Use of Technology in teaching, April 15th – April 18th (2006).
• Efficient presentation skills, March 12th – March 14th (2006).
• Thinking skills development, March 7th – March 9th (2006).
• Management skills development, July 16th – July 19th (2005).
• Taking decisions and solving problems, June 18th – June 21th (2005).
• Management skills development, July 16th – July 19th (2005).
• Time management and work stress, May 28th – May 31ist (2005).

عنوان رسالة الماجستير

تشييد مشتقات اندول شبيهه بعقار الاندوميثاسين

ملخص رسالة الماجستير

A new series of 3-ethyl-2-pheny-1-substituted-indole derivatives 10a-l as indomethacin analogues were synthesized via Fisher indole synthesis reaction of butyrphenone with appropriately substituted phenylhydrazine hydrochloride followed by the addition of the appropriate benzyl or benzoyl derivatives. All the synthesized compounds were evaluated for their anti-inflammatory activity (in vitro, in vivo and ED50) and ulcerogenic liability. The newly synthesized compounds showed higher anti-inflammatory activity, were more selective for COX-2 and less ulcerogenic than the parent drug indomethacin. Compounds (10a-f), containing methanesulphonyl moiety which is expected to act as COX-2 pharmacophore, showed the highest anti-inflammatory and were less ulcerogenic than compounds (10g-l) with no methanesulphonyl moiety.

عنوان رسالة الدكتوراه

ملخص رسالة الدكتوراه