اميرة
اميرة

Amira Mourad Abo-Ypussef

Assistant Professor

Basic Informations

C.V

CURRICULUM VITAE

 

Name: Amira Mourad Hussein Abo-Youssef

Nationality: Egyptian      Date of Birth: July 1, 1973.

Current Position: Lecturer of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.

Home Address: 14 Bashar Ibn Bord ,Nasr City ,Cairo , Egypt.

Office Address: Faculty of Pharmacy, Beni-Suef University, Egypt.

Cellular Phone: +2 01222424884

E-mail Address: amira.aboyoussef@gmail.com

Official E-mail address: amira.aboyousif @pharm .bsu.edu.eg

University Website: www.bsu.edu.eg

 

Educational History

  • Doctor of Philosophy in Pharmaceutical Sciences (Pharmacology and Toxicology) Faculty of Pharmacy, Cairo University, March 2009.

  • Master of Pharmaceutical Sciences (Pharmacology and Toxicology) Faculty of Pharmacy, Cairo University, August 2004.

  • Bachelor of Pharmaceutical sciences, Faculty of Pharmacy, Cairo University,May 1996.

     

    Occupational Background:

  • Lecturer of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Egypt. (since 2009).

  • Assistant Lecturer of Pharmacology and Toxicology, - Faculty of Pharmacy, Beni-Suef University, Egypt. (2004-2009).

  • Demonstrator of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Beni-Suef branch, Egypt. (1997-2004).

     

    Research Interest:

  • Diabetes Mellitus and Metabolic syndrome

  • Behavioral Pharmacology (Alzheimer – depression -anxiety)

  • Lung diseases

  • Liver diseases

  • Studying pharmacological actions of natural products

  • Nanotechnology

Publications:

1- Publications from master and PHD thesis:

  1. Soheir M. El Zalabani, Mona H. Hetta, Samir A. Ross, Amira M. Abo- Youssef, Mohamed A. Zaki and Ahmed S. Ismail. Antihyperglycemic and antioxidant activities and chemical composition of Conyza Dioscoridis (l.) desf. dc. growing in Egypt.Australian Journal of Basic and Applied Sciences.2012;6(10): 257-265.

     

  2. M.R. Nasry, A.M. Abo-Youssef, H.A. Abd El-Latif. Anti-diabetic activity of the petroleum ether extract of Guar gum in streptozotocin-induced diabetic rats: A comparative study. Beni-Suef University Journal of Basic and Applied Sciences. 2013; 2 (1) :51-59.

     

  3. Hany A. Mehany, Amira M. Abo-Youssef, Lamiaa A. Ahmed, El- Shaimaa A. Arafa, Hekma A. Abd El-Latif . Protective effect of vitamin E and atorvastatin against potassium dichromate-induced nephrotoxicity in rats.Beni-Suef University Journal of Basic and Applied Sciences. 2013;2 (2): 96-102.

     

  4. Mai A. Elhemely, Hany A. Omar, Afaf A. Ain-Shoka, Hekma A. Abd El-Latif, Amira M. Abo-Youssef, Gamal A. El Sherbiny. Rosuvastatin and ellagic acid protect against isoproterenol-induced myocardial infarction in hyperlipidemic rats. Beni-Suef University Journal of Basic and Applied Sciences.2014; 3(4): 239-246.

 

  1. Fares EM Ali, Amira M Abo-Youssef, Basim AS Messiha and Ramadan AM Hemeda. Protective effects of quercetin and ursodeoxycholic acid on hepatic ischemia-reperfusion injury in rats. Clinical Pharmacology & Biopharmaceutics.2014; 4:1-7.

     

  2. Ehab A.M. EL-Shoura, Basim A.S. Messiha, Amira M. Abo-Youssef, Ramadan A.M. Hemeida. Modulatory effect of lovastatin on therapeutic efficiency of conventional antidiabetics on pancreatic and cardiovascular complications of diabetes. UK Journal of Pharmaceutical and Biosciences.2015; 3(1), 01-11.

     

  3. Emad H.M. Hassanein, Amira M. Abo-Youssef, Basim A.S. Messiha, Ramadan A.M.Hemeida. Protective effects of montelukast and l-carnitine on cyclophosphamide-induced lung injury. UK Journal of Pharmaceutical and Biosciences.2015; 3 (1):30-36.

     

  4. Mustafa A. Abd Ellraheim, Amira M. Abo-Youssef, Hany A. Omar, Hekma A. Abd El-Latif.Angiotensin inhibitors potentiate the hypoglycemic and antioxidant effects of gliclazide in rats. International Journal of Pharmaceutical Sciences Review and Research. 2015; 31(1): 75-80.

     

  5. Souty M. ShŠarkawi, Amira M. Abo-Youssef, Basim A.S. Messiha, Ali A. Abo-Saif. Effect of ethanol consumption on colon of normal rats as well as rats with experimentally-induced ulcerative colitis. International Journal of Advanced Research.2015; 3 (4):174-185.

     

  6.  W.A.E.-S.I. Khallaf, B.A.S. Messiha, Amira M.Abo - Youssef, N.S.E.-D. El-Sayed. Effect of tempol on lipopolysaccharide induce amyloidogenesis , neuroinflammation. International Journal of Pharmaceutical Sciences Review and Research. 2015;33(2):145-148.

     

  7.  Magy R. Nasry, Amira M. AboYoussef , Hala F. Zaki, Ezz ElDin S. El Denshary.  Effect of caffeic acid and pioglitazone in an experimental model of   metabolic syndrome. International Journal of Scientific and Research Publications.2015; 5 (10):1-10.

     

  8.  Mohamed A Hamzawy, Amira M Abo-Youssef, Heba F Salem,Sameh Mohamed. An additional risk of lung cancer from recurrent exposure to ethyl carbamate (EC) in  balb/c mice.Cancer Science & Therapy.2015 ;7:359-362.

     

  9. Mohammed Ragab Abdel-Aziz Al, Amira Mourad Hussein Abo-Youssef, Basim Anwar Shehata Messiha, Mahmoud Mohamed Khattab. Tempol and perindopril protect against lipopolysaccharide induced cognition impairment and amyloidogenesis by modulating brain-derived neurotropic factor, neuroinflammation and oxido-nitrosative stress. Naunyn-Schmiedeberg's Archives of Pharmacology. 2016; 389:637-656.

  10. Mostafa Assem Mostafa Darwish, Amira M. Abo-Youssef, Marwa M. Khalaf, Ali Ahmed Abo-Saif, Ibrahim G. Saleh, Tamer M. Abdelghany. Vitamin E mitigates cisplatin-induced nephrotoxicity due to reversal of oxidative/nitrosative stress, suppression of inflammation and reduction of total renal platinum accumulation.Journal of Biochemical and Molecular Toxicology.2016; a head of print.DOI: 10.1002/jbt.21833.

 

  1.  Ali H El-Bahrawy; Abdelmetalab Tarhuni; Hogyoung Kim; Venkat Subramaniam; Ilyes Benslimane; Zakaria Y. Abd Elmajeed ; Samuel Okpechi; Mohamed Ghonim; Ramadan A. M.Hemeida; Amira M. Abo-youssef; Gamal A. El-Sherbiny; Ihab T Abdel-Raheem; Jong Kim; Amarjit S. Naura; A. Hamid Boulares. ApoE deficiency promotes colon inflammation and enhances inflammatory potential oxidized-LDL and TNF-α in colon epithelial cells. Bioscience Reports.2016; a head of print. DOI: 10.1042/BSR20160195.

     

  2.  Hassan, Hesham; Mansour, Ahmed; Abo-Youssef, Amira; Elsadek, Bakheet; Messiha, Basim. Zinc oxide nanoparticles as a novel anticancer approach; in vitro and in vivo evidences. Clinical and Experimental Pharmacology and Physiology. 2016; a head of print. DOI: 10.1111/1440-1681.12681.

     

  3.  Mohamed A Hamzawy, Amira M Abo-youssef, Heba F Salem, Sameh Mohamed. Preparation and potential therapeutic application of intratracheal inhalation of temozolomide (TMZ) loaded into gold nanoparticles and/ Or liposomes against urethane induced lung cancer in BALB/c mice. Drug Delivery.2016; a head of print.

     

  4.  Samar M. Hassan, Marwa M. Khalaf , Sawsan A. Sadek, Amira M. Abo-Youssef.

    Protective effects of apigenin and myricetin against cisplatin-induced nephrotoxicity in mice. Pharmaceutical Biology. 2017; 55:766-774.

 

 

 

 

2- Publications single or equal contribution:

  1. Nagwa M. Abdel Gawad and Amira M. Abo -Youssef.Synthesis of some new oxindole derivatives as potential antipsychotic and anticonvulsant agents. International Journal of Pharmacy and Pharmaceutical Sciences.2011; 3 Suppl 3: 213-219.

     

  2. R. Mohammed, S.S. El-Hawary, A.M. Abo-Youssef. Biological investigation of some wild Aizoaceae and Chenopediaceae species growing in Egypt. Journal of Natural Products. 2012;5: 193-206.

     

  3. Amira M. Abo-Youssef , Rabab Mohamed. Effects of Brassica Rapa on fructose-induced metabolic syndrome in rats: A comparative study. International Journal of Pharmaceutical Sciences Review and Research.2013; 21(1):1-5.

     

  4. Amira Mourad Hussein Abo-Youssef, Basim Anwar Shehata Messiha. Beneficial effects of Aloe Vera in treatment of diabetes: Comparative in vivo and in vitro studies. Bulletin of Faculty of Pharmacy, Cairo University.2013; 51 (1):7-112.

     

  5. Messiha BA, Abo-Youssef AM. Protective effects of fish oil, allopurinol, and verapamil on hepatic ischemia-reperfusion injury in rats. Journal of Natural Science, Biology and Medicine.2015;6(2):351-355.

     

  6. Amira M. Abo- Youssef . Protective effect of rosiglitazone, quercetin and their combination on fructose- induced metabolic syndrome in rats. Indian Journal of pharmacology.2015; 47:620-626.

     

  7. Amira M. Abo-Youssef. Possible antidepressant effects of vanillin against experimentally induced chronic mild stress in rats. Beni-Suef University Journal of Basic and Applied Sciences.2016;5 (2):187-192.

     

  8. Asmaa Owis, Amira M.Abo-Youssef, Ahmed Osman. Protective effect of Cordia boissieri A. DC. (Boraginaceae) on metabolic syndrome. Journal of Applied Pharmaceutical Science.2016; 6 (8): 83-89.

     

  9.  Asmaa I. Owis, Amira M. Abo-Youssef, Ahmed H. Osman. Leaves of Cordia boissieri A. DC., as a Potential Source of Bioactive Secondary Metabolites for Protection against Metabolic Syndrome-Induced in Rats. Zeitschrift für Naturforschung C (ZNC). 2016; a head of print. DOI: 10.1515/znc-2016-0073.

     

    Projects

 

1-" Study of the possible protective effects of rosuvastatin and ellagic acid on myocardial infarction”

Hany A Omar, Amira M. Abo-youssef, Mai Abd-Allah Mohammed

 Project Funded by Scientific Research Developing Unit, Beni Suef University.

 

2- “Medicinal Plants as enormous resources for important bioactive secondary metabolites”

Asmaa Owis, Amira M.Abo-Youssef

Project funded by Scientific Research Developing Unit, Beni Suef University.

Conferences Participation

 

  • Poster presented at 52nd Annual Scientific Conference -The Egyptian Society of Pharmacology and Experimental Therapeutics.10th March 2012.

    Anti-diabetic activity of Guar-gum in streptozotocin induced diabetic rats.

    Magy R Nasry, Amira M.Abo-Youssef, Hekma A. Abd el Latif

     

  • Poster presented at: The 50th Congress of the European Societies of Toxicology (EUROTOX) Edinburgh, United Kingdom, September 7-10, 2014.

            Alternative animal model of urethane-induced lung cancer: A pilot    study.  

           Sameh Mohamed A., Amira M. Abo-Youssef, Heba F. Salem, Mohamed A. Hamzawy

    *The abstract was published in Toxicology Letters Journal (IF 3.262), 229S (2014) S40–S252.

  • Poster presented at the 7th European Exhibition of Creativity and Innovation – EUROINVENT, Iasi, Romania, May 14-16 2015.

            Temosome, a novel formula for treatment of lung cancer

     Sameh Mohamed A., Amira M. Abo-Youssef, Heba F. Salem, Mohamed  A. Hamzawy.

·        Posters presented at: 1st International Conference On Health between Nutrition and Treatment. Faculty of Pharmacy Beni-Suef University Beni-Suef, EGYPT August 30-31, 2015:

  1. Anti-ischemic, anti-inflammatory and anti-oxidant mechanisms of sildenafil and coenzyme Q10 against renal ischemia/reperfusion injury in rats.

                Amany Azooz , Amira M. Abo-youssef, Hany A. Omar,    Hekma A. Abd el Latif.

     

  1. Possible protective roles of tempol on oxidative stress in experimentally induced alzheimer’s like in mice

                         Mohamed Ragab , Amira M. Abo-Youssef, Bassim  Messiha, Mahmoud Khattab.

     

General certificates:

  • International Computer driving License (ICDL).

  • National TOEFL PBT.

 

Main managerial responsibilities:

 

  • Member of the Quality Assurance Unit Team, Faculty of Pharmacy, Beni-Suef University who prepared for getting CIQAP (2013).

  • Lecturer in Faculty of Pharmacy and Faculty of Dentistry; Nahda University (NUB).

  • Lecturer in Faculty of Pharmacy; El Arab Medical University, Libya

  • Lecturer in Faculty of Pharmacy, 6th October University.

  • Lecturer in Faculty of Pharmacy; Misr International University (MIU).

  • Lecturer in Faculty of Pharmacy and Faculty of Nursing; Modern University of Technology and Information (MTI)

     

    Membership:

    Member in the Egyptian General Syndicate of Pharmacists

  • Member in Beni-Suef Syndicate of Pharmacists.

     

    Teaching Experience:

  • Teaching and supervising the practical courses of Pharmacology and Toxicology for the undergraduate students (first, Third, fourth & fifth year) in Faculty of Pharmacy, Beni-Suef University general and clinical pharmacy programs.

  • Oral examiner for undergraduate students in Faculty of pharmacy Beni-Suef University and in other public and private universities.

  • Teaching and supervising in Pharmacology and Toxicology for the postgraduate students in Faculty of Pharmacy, Beni-Suef University.

  • Supervising many of M.Sc. and Ph.D. students (Pharmacology and Toxicology).

  • Working as academic advisor for clinical pharmacy program students (since 2009).

  • Supervising the summer training of undergraduate students at Faculty of Pharmacy, Beni-Suef University.

    Scientific Courses:

    Under graduate students

  • Medical terminology

  • Pharmacology (I , II ,III)

  • Biostatistics and Bioassay

  • Toxciology

  • First aid

  • Clinical pharmacology

  • Veterinary Pharmacology

  • Drug therapy (I,II)

  • Drug interactions

  • Physiology

     

    Premaster courses:

  • Drug therapy

  • Toxicometrics

  • Pharmacometrics

  • Immunopharmacology

  • Pathophysiology

     

    Amira Mourad Abo-Youssef

C.V PDF

Master Title

Pharmacological study of protein malnutrition on the pharmacological profile of certain antianxiety drugs in experimental animals

Master Abstract

In the present study the effect of protein malnutrition alone and in presence of diazepam (5mg/Kg) as well as, buspirone (5mg/Kg) were studied in rats after 2 hours, 7 days and 14 days on behavioral and biochemical parameters. Protein malnutrition was induced by restricting the amount of casein in the prepared diet to 7.5 % instead of 20 % in normal protein diet. Induction of protein malnutrition started just after weaning. Three models of behavioral examinations were selected to study the possible effects of protein malnutrition on behavioral responses to drug. These models included swimming test, open field test and conditioned avoidance test. In addition, biochemical parameters were measured in the brain namely, GABA, 5HT, NE and DA.

Master Abstract PDF

PHD Title

Pharmacological study of the possible interactions between certain antidiabetics and selected antiepileptic drug in experimental animals

PHD Abstract

In the present study, both in vivo and in vitro experiments were carried out in order to study the possible interactions between certain antidiabetics and selected antiepileptic agent in experimental animals. The purpose of the in vitro experiments was to investigate the possible effects of gliclazide (10, 20, 40 µmol/l), aqueous extract of Morus alba leaves ( 10, 20, 40 µg/ml) , aqueous extract of ginseng radix ( 25, 50, 100 µg/ml) and carbamazepine ( 10, 20, 40 µmol/l), alone and in combination on basal ( glucose 3 mmol/l) and glucose 16.7 mmol/l -stimulated insulin secretion using isolated rat pancreatic islets technique. The purpose of the in vivo experiments was to investigate the possible effects of gliclazide (10 mg/kg), carbamazepine (50 mg/kg), aqueous extract of Morus alba leaves (100 mg/kg) and aqueous extract of ginseng radix (100 mg/kg) alone and in combination in streptozotocin ( 50 mg/kg)- induced diabetic rats. The effects of these treatments on serum glucose and insulin levels were investigated after two weeks of daily dose administration. The effects on serum glucose and insulin levels and insulinogenic index during oral glucose tolerance test were also studied after two weeks of daily dose administration. The effects of the aforementioned treatments on liver glycogen content and blood MDA, nitric oxide and GSH were also investigated.

PHD Abstract PDF

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