Basic Informations

C.V

shimaa muhammad essam

Master Title

prenatal development of salivary glands in rabbit

Master Abstract

Summary The present work was conducted on 55 normal and apparently healthy New-Zealand rabbit embryos and fetuses from 11 days post conception till full term. The whole fetuses from 11 days up to full term were prepared to obtain 3-5 um thick; serial and step serial paraffin sections of head region as a whole or the salivary gland and stained by different stains to be studied by light microscope. The present work revealed the prenatal development of the major salivary glands in New-Zealand rabbit fetuses. I-The submandibular salivary gland: The primordium of submandibular salivary gland was firstly appeared in 12 days-old rabbit fetuses. It appeared as bilateral solid epithelial buds invaginated from the linguo-gingival groove at the base of the developing tongue. At the13th day of fetal life, the submandibular buds grew deeply into underlying mesenchymal tissue forming solid epithelial cords. At the 15th day, the developing cords continued their deep down growth and showed compact terminal bulges forming the primitive acini which surrounded by large amount of primitive stroma with many fibroblasts and mesenchymal cells. The primitive ducts began to be canalized at the 18th day of prenatal life. They were lined by one to two layers of cuboidal to columnar cells housing rounded or oval nuclei surrounded respectively by pale basophilic cytoplasm. The acini were still illuminized. On reaching the 22nd day, the mesenchymal tissue became differentiated into primitive capsule and trabeculae that divided the gland into different lobes and lobules. From 27 days of intrauterine life till the end of prenatal life, submandibular gland became highly developed and became typical compound tubulo-acinar gland. The glandular lobules were increased on the expense of the interstitial tissue. The stroma became fully developed

PHD Title

PHD Abstract