أ.د. فيبي فرج الله لمعي سليمان

الكيمياء العضويه الصيدلية

1) Pyrazolo[3,4-d]pyrimidine-based dual EGFR T790M/HER2 inhibitors: Design, synthesis, structure–activity relationship and biological activity as potential antitumor and anticonvulsant agents, Phoebe F Lamie, Asmaa M El-Kalaawy, Noha S Abdel Latif, Laila A Rashed, John N Philoppes, European Journal of Medicinal Chemistry, 214, 2021, 113222-113243. https://doi.org/10.1016/j.ejmech.2021.113222

2) Novel N-methylsulfonyl-indole derivatives: biological activity and COX-2/5-LOX inhibitory effect with improved gastro protective profile and reduced cardiovascular risks, John N. Philoppes, Mohamed A. Abdelgawad, Mohammed A. S. Abourehab, Mohamed Sebak, Mostafa A. Darwish and Phoebe F. Lamie, Journal of Enzyme Inhibition and Medicinal Chemistry, 38 (1), 2023, 246-266. https://doi.org/10.1080/14756366.2022.2145283 

3) Design, synthesis and in silico insights of novel 1,2,3-triazole benzenesulfonamide derivatives as potential carbonic anhydrase IX and XII inhibitors with promising anticancer activity, Marwa M. Abdelhakeem, Martha M Morcoss, Dina A. Hanna, Phoebe F. Lamie, Bioorganic Chemistry 144, 2024, 107154. https://doi.org/10.1016/j.bioorg.2024.107154