أ.م.د. مها محمد عبد الفتاح حامد
 

المنصب الأكاديمي: 
أستاذ مساعد بقسم الأدوية والسموم                                                     

مناصب أخري:
1- عضو في الارشاد الاكاديمي للبرنامج الاكلينيكى 2018-2020
2- عضو في لجنة البحث العلمي بوحدة ضمان الجودة 2016-2020.
3- منسق لجنة البحث العلمي بوحدة ضمان الجودة2020 -2022.
4- مدير وحدة الازمات والكوارث 2020-2021. 
5- مساعد منسق البرنامج العام فارم دى 2021-2022. 
6- عضو فى لجنة اخلاقيات البحث العلمى (اخلافيات التعامل مع حيوانات التجارب) 2022- 2023.
7- نائب مدير وحدة الجودة 2022- 2023.
8- منسق لجنة اخلاقيات البحث العلمى (اخلافيات التعامل مع حيوانات التجارب) 2023- 2024.
9- مدير وحدة الجودة 2023- حتى تاريخه
10- رئيس قسم المستحضرات الطبية والعطرية والدوائية بمعهد ابحاث النباتات الطبية والعطرية والدوائية سبتمبر 2024. 

الأتصال:
    
mahamohammed@pharm.bsu.edu.eg
 
الدرجات العلمية:




2011          بكالوريوس في العلوم الصيدلية                كلية الصيدلة            جامعة بني سويف             مصر
2015          ماجستير في الأدوية والسموم                   كلية الصيدلة            جامعة بني سويف             مصر





2018         دكتوراه في الأدوية والسموم                    كلية الصيدلة            جامعة بني سويف             مصر


عنوان رسالة الماجستير:
Study of the possible protective effects of selected agents in experimentally-induced bronchial asthma in rats.

عنوان رسالة الدكتوراه:
Pharmacological study of the possible potential effects of selected agents against cerebral ischemia/reperfusion induced experimentally in rats

المهام التدريسية: 
Pharmacology 1
Pharmacology 2
Medical Terminology 
Pharmacology 3
Basic pharmacology 
Clinical pharmacology 
Therapeutics 
Toxicology 
Drug interactions 
Bioassay 
Toxicometrics
Pharmacometrics 
Experimental pharmacology 

أبحاث مختارة: 
1) Abdel-Fattah MM, Salama AAA, Shehata BA, Ismaiel IE. The potential effect of the angiotensin II receptor blocker telmisartan in regulating OVA-induced airway remodeling in experimental rats. Pharmacological Reports 2015; 67(5): 943-951. 
2) Abdel-Fattah MM, Messiha BAS, Salama AAA. Assessment of the mechanistic role of cinnarizine in modulating experimentally-induced bronchial asthma in rats. Pharmacology 2015; 96(3-4): 167-174.
3) Abdel-Fattah MM, Messiha BAS, Mansour AM. Modulation of brain ACE and ACE2 may be a promising protective strategy against cerebral ischemia/reperfusion injury: an experimental trial in rats. Naunyn-Schmiedeberg's Archives of Pharmacology journal 2018.
4) Ahmed H.Abdelazeem, Asmaa G.Safi El-Din, Maha M.Abdel-Fattah, Noha H.AminaSamir M.El-Moghazy, Mohammed T.El-Saadia. Discovery of novel urea-diarylpyrazole hybrids as dual COX-2/sEH inhibitors with improved anti-inflammatory activity and highly reduced cardiovascular risks. European Journal of Medicinal Chemistry 2020.
5) Khaled RA Abdellatif, Eman KA Abdelall, Heba AH Elshemy, El‐Shaymaa El‐Nahass, Maha M Abdel‐Fattah, Yasmin YM Abdelgawa New indomethacin analogs as selective COX‐2 inhibitors: Synthesis, COX‐1/2 inhibitory activity, anti‐inflammatory, ulcerogenicity, histopathological, and docking studies. Archiv der Pharmazie. 2021.
6) Maha M.Abdel-Fattah, Abdel Nasser.A.M.Elgendy, Wafaa R.Mohamed. Xanthenone, ACE2 activator, counteracted gentamicin-induced nephrotoxicity in rats: Impact on oxidative stress and ACE2/Ang-(1–7) signaling. Life science. 2021.
7) Noha H Amin, Mohammed IA Hamed, Maha M Abdel-Fattah, Ahmed HA Abusabaa, Mohammed T El-Saadi. Design, synthesis and mechanistic study of novel diarylpyrazole derivatives as anti-inflammatory agents with reduced cardiovascular side effects. Bioorganic Chemistry. 2021.
8) Ahmed M.Sayed, Maha M.Abdel-Fattah, Hany H.Arab, Wafaa R.Mohamed, Emad H.M.Hassanein . Targeting inflammation and redox aberrations by perindopril attenuates methotrexate-induced intestinal injury in rats: Role of TLR4/NF-κB and c-Fos/c-Jun pro-inflammatory pathways and PPAR-γ/SIRT1 cytoprotective signals. Chemico-Biological Interactions. 2022.
9) Maha M Abdel-Fattah, Abeer AA Salama, Basim AS Messiha. Immunomodulatory and anti-inflammatory effects of N-acetylcysteine in ovalbumin-sensitized rats. Beni-Suef University Journal of Basic and Applied Sciences. 2022.
10) Phoebe F Lamie, Maha M Abdel-Fattah, John N Philoppes. Design and synthesis of new indole drug candidates to treat Alzheimer’s disease and targeting neuro-inflammation using a multi-target-directed ligand (MTDL) strategy. Journal of enzyme inhibition and medicinal chemistry, 2022.
11) Khaled RA Abdellatif, Eman KA Abdelall, Phoebe F Lamie, Madlen B Labib, Marwa M Abdelhakeem, Maha M Abdel-Fattah, El-Shaymaa El-Nahaas. Novel pyrazole-oxadiazole hybrids possessing methanesulphonyl pharmacophore with good gastric safety profile: Design, synthesis, cyclooxygenase inhibition, anti-inflammatory activity and histopathological studies. Journal of Molecular Structure, 2022.
12) Mohammed E. Abo‑El Fetoh, · Maha M. Abdel‑Fattah, · Wafaa R. Mohamed, · Laila A. A. Ramadan, ·Hassan Afify. Cyclooxygenase 2 activates EGFR–ERK1/2 pathway via PGE2 mediated ADAM 17 signaling in testosterone induced benign prostatic hyperplasia. Inflammopharmacology, 2023.
13) Maha M. Abdel-Fattah, Emad H. M. Hassanein, Ahmed M. Sayed,Shuruq E. Alsufyani, Azza A. K. El-Sheikh, Hany H. Arab 4, Wafaa R. Mohamed. Targeting SIRT1/FoxO3a/Nrf2 and PI3K/AKT Pathways with Rebamipide Attenuates Acetic Acid-Induced Colitis in Rats. Pharmaceuticals, 2023.
14) Maha M. Abdel-Fattah, Wafaa R. Mohamed, Emad H.M. Hassanein, Hany A. Arab, El-shaimaa A. Arafa. Role of NF-κB/ICAM-1, JAK/STAT-3, and apoptosis signaling in the anticancer effect of tangeretin against urethane-induced lung cancer in BALB/c mice. Life Sciences, 2023.
15) Noha H Amin, Mohammed T El-Saadi, Maha M Abdel-Fattah, Asmaa A Mohammed, Eman G Said. Development of certain aminoquinazoline scaffolds as potential multitarget anticancer agents with apoptotic and anti-proliferative effects: Design, synthesis and biological evaluation. Bioorganic Chemistry, 2023.
16) Maha M Abdel-Fattah, Mohammed E Abo-El Fetoh, Hassan Afify, Laila AA Ramadan, Wafaa R Mohamed. Probenecid ameliorates testosterone-induced benign prostatic hyperplasia: Implications of PGE-2 on ADAM-17/EGFR/ERK1/2 signaling cascade. Journal of Biochemical and Molecular Toxicology, 2023.
17) Mohammed E. Abo-El Fetoh, Maha M. Abdel-Fattah, Hassan Afify, Laila A. A. Ramadan, Wafaa R. Mohamed. Review on EGFR–ERK1/2 signaling cascade: Implications on cell proliferation in health and disease. Egyptian Pharmaceutical Journal, 2023, in press. 
18) Eman K. A. Abdelall, Heba A.H. Elshemy, John N. Philoppes, Maha M. Abdel-Fattah, El-Shaymaa El-Nahaas, Rabab R. Mahmoud. Development of safe and antioxidant COX-2 inhibitors; Synthesis, molecular docking analysis and biological evaluation of novel pyrrolizine 5-carboxamides. Bioorganic Chemistry.2024, vol 143, 107098.
19) Maha M Abdel‐Fattah, Ahmed Mamdouh Ahmed, Rabeh Khairy Saleh, Basim Anwar, Shehata Messiha, Remon Roshdy Rofaeil. The protective effect of pregabalin and xanthenone on testicular ischemia/reperfusion injury in rats. Fundamental & Clinical Pharmacology. 2024, e13027.
20) Maha M Abdel‐Fattah, Ahmed Mamdouh Ahmed, Rabeh Khairy Saleh, Basim Anwar, Shehata Messiha, Remon Roshdy Rofaeil. The protective effect of pregabalin and xanthenone on testicular ischemia/reperfusion injury in rats. Fundamental & Clinical Pharmacology. 2024, e13027.
21) Ahmed M Shawky, Faisal A Almalki, Hayat Ali Alzahrani, Ashraf N Abdalla, Bahaa GM Youssif, Nashwa A Ibrahim, Mohammed Gamal, Hany AM El-Sherief, Maha M Abdel-Fattah, Ahmed A Hefny, Ahmed H Abdelazeem, Ahmed M Gouda. Covalent small-molecule inhibitors of SARS-CoV-2 Mpro: Insights into their design, classification, biological activity, and binding interactions. European Journal of Medicinal Chemistry. 2024, 116704.

روابط أخري:
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