Clinical Program Courses - PharmD

POC 101 - Pharmaceutical Organic Chemistry I (2+1)
The objective of this course is to provide students with the basic knowledge in pharmaceutical organic chemistry, which will serve as fundamentals for other courses offered during subsequent semesters. This course involves Electronic structure of atom, alkanes [nomenclature, synthesis and reactions (free radical reactions)], and cycloakanes. Stereochemistry (Optical isomers, racemic modification, nomenclature of configurations). Alkenes, alkadienes and alkynes. Alkyl halides (nomenclature, preparation and chemical reactions (SN1, SN2, E1, E2). Arenes and aromatic compounds (Kekule structure, Huckel rule, Electrophilic aromatic substitution and orientation).

POC 202 - Pharmaceutical Organic Chemistry II ( 2 +1 )
This course involves different classes of organic compounds: aryl halides, Alcohols, Phenols, ethers & epoxides, aldehydes, ketones, carboxylic acid & acid derivatives, sulphonic acids, and nitrogenous compounds.

POC 303 - Pharmaceutical Organic Chemistry III ( 2+ 1 )
This course involves: carbohydrates, amino acid & peptides, polynuclear and heterocyclic chemistry. In addition, it provides an introduction about the use of different spectroscopic tools, including UV, infrared (IR), nuclear magnetic resonance (NMR) and mass spectrometry (MS) for the structural elucidation of organic compounds.

POC E04 - Advanced Drug Structural Determination (1+1)
Spectral technique, using of spectroscopic methods in drug determination, UV (Electronic Transitions, Beer-Lambert Law, Sample Preparation, Common Transitions and Functional Groups, Conjugation, Woodward-Fieser Rules), IR (Stretching and Bending; Hooke’s Law, Sample Preparation, Spectral Range; Hydrocarbons, Alcohols, Carbonyls; Structural Insight Through Changes Playing with k / bond order), NMR (1H NMR, 13C NMR) and Mass spectroscopy (Electron Impact MS, Fragmentation, High Resolution MS, Softionization techniques (ESI, CI, MALDI, etc.).