Research Article

Morphological pathology of bovine ovarian abnormalities in correlation to uterine changes

Ahmed Khaled a, El-Shaymaa El-Nahass, Mahmoud M. Hussien, Khalid A. El-Nesr
Department of Pathology, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef 62511, Egypt.

Abstract

Female genital tracts of six to eight years Baladi cows (n=30) were collected from Belevia abattoir of Beni-Suef province during the period from March 2016 to May 2016 to investigate ovarian abnormalities and uterine changes in cattle based on histopathology. Prevalence rates of granulosa cell tumors were 26.67% and 38.89% in right and left ovaries, respectively. Follicular cysts could be detected in both ovaries with percentages of 50.0% and 44.44%, respectively. The most predominant pathological lesions in ovarian medulla were hyalinosis of blood vessels and mononuclear cell infiltration. The main uterine pathological alterations were endometritis associated with degenerative changes and necrosis in the endometrial linings in most cases (n=25), endometriosis (n=13). Variable degrees of congestion from moderate (n=25) to highly congested (n=5) were elucidated. Perivascular cuffing (n=2) and perivascular fibrosis (n=3) of uterine blood vessels could be detected. Immunohistochemically, granulosa cell tumors were positive to vimentin and negative to inhibin.

Keywords

cattle, ovaries, granulosa cell tumors, histopathology, immunohistochemistry, cyctic follicles